C-Peptide

The middle segment of proinsulin that is between the N-terminal B-chain and the C-terminal A-chain. It is a pancreatic peptide of about 31 residues, depending on the species. Upon proteolytic cleavage of proinsulin, equimolar INSULIN and C-peptide are released. C-peptide immunoassay has been used to assess pancreatic beta cell function in diabetic patients with circulating insulin antibodies or exogenous insulin. Half-life of C-peptide is 30 min, almost 8 times that of insulin.

Also Known As:

C-Peptide, Proinsulin; Connecting Peptide; C Peptide; C Peptide, Proinsulin; Proinsulin C Peptide; Proinsulin C-Peptide

Hormones, Hormone Substitutes, and Hormone Antagonists
- Hormones: 82104
  - Peptide Hormones: 1361
    - Pancreatic Hormones: 116
      - Insulins: 668
        Proinsulin: 1203
        C-Peptide: 4788
Amino Acids, Peptides, and Proteins: 1
- Peptides: 84029
  - Peptide Hormones: 1361
    - Pancreatic Hormones: 116
      - Insulins: 668
        Proinsulin: 1203
        C-Peptide: 4788

Daniela Gotera Selected Research

Daniela Gotera Research Topics

Disease

Drug/Important Bio-Agent (IBA)